Accuracy of 177Lu activity quantification in SPECT imaging: a phantom study
نویسندگان
چکیده
منابع مشابه
Accuracy of 177Lu activity quantification in SPECT imaging: a phantom study
BACKGROUND The aim of the study is to assess accuracy of activity quantification of 177Lu studies performed according to recommendations provided by the committee on Medical Internal Radiation Dose (MIRD) pamphlets 23 and 26. The performances of two scatter correction and three segmentation methods were compared. Additionally, the accuracy of tomographic and planar methods for determination of ...
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The purpose of this study is to investigate the optimal reference geometry for gamma camera calibration. Yet another question of interest was to assess the influence of the number of 3D Ordered Subsets Expectation Maximization (3D-OSEM) updates on activity quantification for SPECT imaging with 177Lu. The accuracy of 177Lu activity quantification was assessed both in small and in large objects. ...
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BACKGROUND In targeted radionuclide therapy (TRT), accurate quantification using SPECT/CT images is important for optimizing radiation dose delivered to both the tumour and healthy tissue. Quantitative SPECT images are regularly reconstructed using the ordered subset expectation maximization (OSEM) algorithm with various compensation methods such as attenuation (A), scatter (S) and detector and...
متن کاملDetermination of optimum filter in myocardial SPECT: A phantom study
Background: In myocardial perfusion SPECT imaging, images are degraded by photon attenuation, the distance-dependent collimator, detector response and photons scatter. Filters greatly affect quality of nuclear medicine images Materials and Methods: A phantom simulating heart left ventricle was built. About 1mCi of 99mTc was injected into the phantom. Images were taken from this phantom. Some fi...
متن کاملIn vivo quantification of 177Lu with planar whole-body and SPECT/CT gamma camera imaging
BACKGROUND Advances in gamma camera technology and the emergence of a number of new theranostic radiopharmaceutical pairings have re-awakened interest in in vivo quantification with single-photon-emitting radionuclides. We have implemented and validated methodology to provide quantitative imaging of (177)Lu for 2D whole-body planar studies and for 3D tomographic imaging with single-photon emiss...
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ژورنال
عنوان ژورنال: EJNMMI Physics
سال: 2017
ISSN: 2197-7364
DOI: 10.1186/s40658-016-0170-3